If the graphics card is seated properly, and your computer still will not boot up with the graphics card inserted, the graphics card will most likely need to be serviced or replaced.
Many motherboards have their own onboard graphics card that you can use if your dedicated graphics card isn’t putting out a usable signal. If you just need to update your drivers, you can temporarily switch to the graphics display on the motherboard to update your graphics drivers. Alternatively, if you started experiencing problems after updating your graphics card, try downloading older drivers from the manufacturer’s website and installing those. For some older graphics cards, new drivers may do more harm than good. If you recently switch graphic card brands, be sure to uninstall the old graphics card drivers before installing the new graphics card. You can use a third-party app to completely uninstall the graphics drivers without leaving any trace.
In order to fully clean your graphics card, you will most likely need to remove the fan and heat sink casing.
Also check the input and output ports on the back of the card to make sure they are not rusted or corroded. If you determine that your graphics card needs repair, be aware that professional repair may cost more than the cost of purchasing a new graphics card.