Pokeweed is toxic when you eat it uncooked, but it’s not dangerous to touch. However, some people are sensitive to the sap from the plant, so you’re best off wearing gloves if you want to avoid irritating your skin. [1] X Research source
Manual removal of pokeweed can be difficult once it is fully grown, since pokeweed can grow up to 10 feet (3. 0 m) tall. If the pokeweed is fully mature, you may need to employ multiple weed removal solutions to get the deep taproot out. [2] X Research source
How long this takes to kill the pokeweed depends on how deep the taproot goes, but it may take a few growing seasons.
Cover the plants with cardboard sheets and then lay compost over them. Over time, the cardboard will break down into the soil. Lay stacks of newspaper down and then cover the weeds in landscape fabric. The newspaper will decompose over time and the fabric will keep new weeds from growing. Cover the entire area in mulch. This will keep weeds from growing and provide you with some elegant land cover.
This solution has varying results depending on just how strong the taproot is. However, it’s an organic and low-impact option so it’s worth a shot if you’re trying to avoid harsher chemicals.
Horticultural vinegar is distinct from household white vinegar, which is only 5% acetic acid. Just know, this will destroy the soil and concrete around the pokeweed, too. Horticultural vinegar is strong stuff. Keep horticultural vinegar off of your skin, since it can cause your skin to blister. Keep it out of your eyes, since there’s a chance it can cause blindness.
Glyphosate is the main ingredient in Roundup, although there are plenty of products out there that contain glyphosate. 2,4-D is shorthand for 2,4-Dichlorophenoxyacetic acid. Any herbicide with the word “Amine” on the label is a 2,4-D-based herbicide. [7] X Trustworthy Source United States Environmental Protection Agency Independent U. S. government agency responsible for promoting safe environmental practices Go to source Keep in mind, commercial herbicide will kill any plants or grass it comes in contact with.