Taking Prolia can be potentially harmful for people with kidney disease, weak immune systems, thyroid/parathyroid problems, stomach or intestinal problems, dental surgery or tooth removal surgery, or allergies to denosumab (an ingredient in the medication) or latex. Let your doctor and dentist know if you have jaw problems while on Prolia. You may need a dental exam before you can begin Prolia as well. [2] X Research source
If you feel uncomfortable administering the injection yourself, simply go to your healthcare provider each time you need a dose. They will be happy to do it for you.
Don’t try to warm the syringe by using a heat source (like a microwave or hot water). Let it warm up naturally. Heating up the syringe can compromise the medication or even cause the syringe to crack. Be sure that you don’t expose the syringe to direct sunlight while you wait for it to warm up as sunlight can contaminate the medication inside the syringe.
You should also discard the syringe if the medicine is past its expiration date, which will be printed on the syringe label.
For an upper arm injection, another person will have to administer the shot. You cannot do it to yourself in this location. For an abdominal injection, you can choose any area except for a 2 in (5. 1 cm) radius right around your belly button.
Try to get a good couple of inches of skin pulled up slightly away from your body for an effective subcutaneous injection.
You should never reuse or recycle used syringes. If you don’t have a sharps disposal container, contact your healthcare provider to ask about safe disposal of used syringes.
Make sure to use reliable birth control if you are on Prolia. If you are taking Prolia and you become pregnant, stop the treatment immediately and consult with your doctor.
Contact your doctor immediately if you notice any of the following symptoms while using Prolia: muscle spasms or cramps; numbness or tingling in your fingers, toes, or around your mouth; seizures; confusion; or loss of consciousness. You should also replenish your vitamin D levels before using Prolia if you have a deficiency. While you’re using Prolia, continue any calcium or vitamin D supplements you’ve been taking.
Place the entire carton in the refrigerator to protect the medication from exposure to light.